Familial hypercholesterolaemia: underdiagnosed and undertreated
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چکیده
منابع مشابه
Familial hypercholesterolaemia: underdiagnosed and undertreated.
Autosomal dominant familial hypercholesterolaemia (FH) is the most common inherited disorder known to cause premature coronary heart disease in people of European descent. The estimated prevalence of FH is 1 in 500, and heterozygous FH carries a high risk of premature coronary disease if left untreated (.50% risk in men by the age of 50 and .30% in women by 60 years). However, the condition is ...
متن کاملFamilial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease
AIMS The first aim was to critically evaluate the extent to which familial hypercholesterolaemia (FH) is underdiagnosed and undertreated. The second aim was to provide guidance for screening and treatment of FH, in order to prevent coronary heart disease (CHD). METHODS AND RESULTS Of the theoretical estimated prevalence of 1/500 for heterozygous FH, <1% are diagnosed in most countries. Recent...
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متن کاملFamilial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease Consensus Statement of the European Atherosclerosis Society
Børge G. Nordestgaard1*, M. John Chapman2*†, Steve E. Humphries3†, Henry N. Ginsberg4, Luis Masana5, Olivier S. Descamps6, Olov Wiklund7, Robert A. Hegele8, Frederick J. Raal9, Joep C. Defesche10, Albert Wiegman10, Raul D. Santos11, Gerald F. Watts12, Klaus G. Parhofer13, G. Kees Hovingh10, Petri T. Kovanen14, Catherine Boileau15, Maurizio Averna16, Jan Borén17, Eric Bruckert18, Alberico L. Cat...
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ژورنال
عنوان ژورنال: European Heart Journal
سال: 2008
ISSN: 0195-668X,1522-9645
DOI: 10.1093/eurheartj/ehn448